Funding Opportunities
The goal of PASA is to fund research for developing new medications that can improve treatment outcomes for alcohol and substance use disorders (ASUD); especially as related to post-traumatic stress disorder (PTSD) and other psychological disorders. New RFA cycles occur approximately every 12-18 months, and the exact number and type of studies approved during each solicitation period will depend on the quantity and quality of applications received and amount of available funding. For more information or questions about this funding opportunity, email PASA_RFA@rti.org.

Most Recent Funding Opportunities

  • Small-cost and short-duration planning award concerning a specific compound or combination of compounds; to determine the clinical development plan and associated clinical trial(s) needed to advance the compound (or combination of compounds) to FDA approval for ASUD treatment.
  • Soliciting for planning awards under Aims 2 and 3: human participant clinical trials.
  • Timeline:
    • Letter of Intent (LOI): 6/30/2023
    • Full Application Deadline: 7/14/2023
  • Full study implementation awards for proof-of-principle pre-clinical animal research to determine which compounds are most appropriate for human research trials. Using animal models, medications will be assessed to determine if they reduce the aberrant behaviors in models of ASUD comorbid with PTSD or other psychological disorders and potential dosages of these medications can then be estimated for human studies.
  • Soliciting for research under Aim 1: pre-clinical animal research studies.
  • Timeline:
    • LOI: 6/30/2023
    • Full Application Deadline: 7/28/2023
  • Full study implementation awards for proof-of-principle non-clinical research to identify a pool of compounds most appropriate for additional research. The non-clinical research is intended to increase the potential pool of compounds for investigation in subsequent pre-clinical studies and clinical trials. Approaches to identifying promising compounds for development or repurposing studies that leverage large-scale data through computational-based analysis include but are not limited to in silico and augmented intelligence research.
  • Soliciting for research under Aim 1: non-clinical basic research studies.
  • Timeline:
    • LOI: 6/30/2023
    • Full Application Deadline: 7/28/2023
  • Expansion award to support the continued research of highly impactful studies that were previously or currently are funded by PASA.
  • Soliciting for research under all Aims: non-clinical basic research studies, pre-clinical animal research studies, or clinical trials.
  • Timeline:
    • LOI: 6/30/2023
    • Full Application Deadline: 7/14/2023
NOTE: LOIs are for planning purposes; no response from PASA is required to proceed with the full application.
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